研究業績 2007 
　Original Paper
　
 
Characterization of GATA-1+ hemangioblastic cells in the mouse embryo. 
Yokomizo T, Takahashi S, Mochizuki N, Kuroha T, Ema M, Wakamatsu A, Shimizu R, Ohneda O, Osato M, Okada H, Komori T, Ogawa M, Nishikawa S, Ito Y, and Yamamoto M.
EMBO J    26, 184-96  (2007)
 
Shear stress stabilizes NF-E2 related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species. 
Warabi E, Takabe W, Minami T, Inoue K, Itoh K, Yamamoto M, T Ishii T, Kodama T, and Noguchi N.
Free Rad Biol Med    42, 260 − 269  (2007)
 
Inchinkoto, an herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers. 
Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y and Suzuki H.
Am J Physiol Gastrointestinal Liver Physiol   Epub ahead of print,   (2007)
 
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.  
Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, and Kensler TW.
Mol Cancer Therapeutics   1, 54-62  (2007)
 
Carcinogenesis and transcriptional regulation through Maf recognition elements. 
Motohashi H, and Yamamoto M.
Cancer Sci   98(2), 135-9  (2007)
Review
 
Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo [4,5-f] quinoline. 
Kitamura Y, Umemura T, Kanki K, Kodama Y, Kitamoto S, Saito K, Itoh K, Yamamoto M, Masegi T, Nishikawa A, and Hirose M.
Cancer Sci   98, 19-24  (2007)
 
Does K-11706 enhance performance and why?  
Imagawa S, Matsumoto K, Horie M, Ohkoshi N, Nagasawa T, Doi T, Suzuki N, and Yamamoto M.
Int J Sports Med   in press,   (2007)
 
Functional polymorphisms in the transcription factor NRF2 increase the risk of acute lung injury.  
Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, Lanken PN, Aplenc R, Yamamoto T, Yamamoto M, Cho, H-Y, and Kleeberger SR.
FASEB J   ,  in press  (2007)
 
Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia.  
Asou N, Yanagida M, Huang L, Yamamoto M, Shigesada K, Mitsuya H, Ito Y, and Osato M.
Blood    109, 4023-4027  (2007)
 
Cell cycle-dependent oscillation of GATA2 expression in hematopoietic cells.  
Koga S, Yamaguchi N, Abe T, Minegishi M, Tsuchiya S, Yamamoto M, and Minegishi N.
Blood    109, 4200-4208  (2007)
 
Dynamic regulation of Gata factor levels is more important than their identity.  
Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindern M, Ohneda K, Grosveld F, Yamamoto M, and Philipsen S.
Blood   109, 5481-5490  (2007)
 
Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.  
Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, and Yamamoto M.
Biochem J   404, 459-466  (2007)
 
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.  
Khandekar M, Brandt W, Zhou Y, Dagenais S, Glover TW, Suzuki N, Shimizu R, Yamamoto M, Lim K-C, and Engel JD.
Development   139, 1703-1712  (2007)
 
Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4. 
Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, Chen YT, Chang C, Yamamoto M, Tanimoto K, Engel JD.
EMBO J   26(9), 2295-2306  (2007)
 
GATA-1 self-association controls erythroid development in vivo.  
Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K, and Yamamoto M.
J Biol Chem   282, 15862-15871  (2007)
 
Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.  
Shah ZA, Li RC, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
Neuroscience   147, 53-59  (2007)
 
Enhanced spontaneous and benzo[a]pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice.  
Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T and Yamamoto M.
Cancer Res    67, 5643-5648  (2007)
 
Role of Nrf2 in protection against intracerebral hemorrhage injury in mice.  
Wang J, Fields J, Zhao C, Langer J, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore´ S.
Free Rad Biol Med   43(3), 408-14  (2007)
 
Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis.  
Iida K, Itoh K, Maher JM, Kumagai Y, Oyasu R, Mori Y, Fukushima S, Shimazui T, Akaza H, and Yamamoto M.
Carcinogenesis   in press,   (2007)
 
Regulation of GATA1 gene expression.  
Kobayashi M, and Yamamoto M.
J Biochem (Tokyo)   Jun 13,   (2007)
Review

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