| Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene. | | Canet MJ, Merrell MD, Harder BG, Maher JM, Wu T, Lickteig AJ, Jackson JP, Zhang DD, Yamamoto M, Cherrington NJ. | Drug Metab Dispos   43(1), 93-99  (2015) | | |
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| DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosyl methionine-producing metabolic pathway. | | Nishikawa K, Iwamoto Y, Kobayashi Y, Katsuoka F, Kawaguchi S-i, Tsujita T, Nakamura T, Kato S, Yamamoto M, Takayanagi H, and Ishii M. | Nature Med   21(3), 281-287  (2015) | | |
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| MAFG is a transcriptional repressor of bile acid synthesis and metabolism. | | de Aguiar Vallim, TQ, Tarling, EJ, Ahn H, Hagey LR, Romanoski CE, Lee R, Graham M, Motohashi H, Yamamoto M, and Edwards PA. | Cell Metabolism   21(2), 298-310  (2015) | | |
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| Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis. | | Goto M, Kitamura H, Alam MM, Ota N, Haseba T, Akimoto T, Shimizu A, Takano-Yamamoto T, Yamamoto M, Motohashi H. | Genes Cells   20(6), 464-480  (2015) | 大学院生後藤まきさんの論文です。 | |
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| Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation. | | Keleku-Lukwete N, Suzuki M, Otsuki A, Tsuchida K, Katayama S, Hayashi M, Naganuma E, Moriguchi T, Tanabe O, Engel JD, Imaizumi M, Yamamoto M. | Proc Natl Acad Sci U S A.   112(39), 12169-12174  (2015) | 大学院生Nadineさんの論文です。 | |
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| Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon. | | Rajendran P, Dashwood WM, Li L, Kang Y, Kim E, Johnson G, Fischer KA, Löhr CV, Williams DE, Ho E, Yamamoto M, Lieberman DA, Dashwood RH. | Clin Epigenetics.   7(1),   (2015) | | |
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| Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response. | | Saito R, Suzuki T, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Furusawa Y, Negishi T, Ichinose M, Yamamoto M. | Mol Cell Biol.    36(2), 271-284  (2015) | 大学院生斎藤良太さんの論文です。 | |
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| Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients. | | Kanamori M, Higa T, Sonoda Y, Murakami S, Dodo M, Kitamura H, Taguchi K, Shibata T, Watanabe M, Suzuki H, Shibahara I, Saito R, Yamashita Y, Kumabe T, Yamamoto M, Motohashi H, and Tominaga T. | Neuro Oncol   17, 555-565  (2015) | | |
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| CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. | | Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, Yamamoto M, Tong Q, Teng W, Qu W, Zhang Q, Andersen ME, and Pi J. | Antioxid Redox Signal    22, 819-831  (2015) | | |
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| 12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function. | | Rothe T, Gruber F, Uderhardt S, Ipseiz N, Rössner S, Oskolkova O, Blüml S, Leitinger N, Bicker W, Bochkov VN, Yamamoto M, Steinkasserer A, Schett G, Zinser E, and Krönke G. | J Clin Invest    125, 1944-1954  (2015) | | |
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| GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow. | | Ohmori S, Moriguchi T, Noguchi Y, Ikeda M, Kobayashi K, Tomaru N, Ishijima Y, Ohneda O, Yamamoto M, and Ohneda K. | Blood   125, 3306-3315  (2015) | | |
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| Compound mouse mutants of bZIP transcription factors MafG and MafK reveal a regulatory network of non-crystallin genes associated with cataract. | | Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, and Lachke SA. | Hum Genet    134, 717-735  (2015) | | |
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| Hypoxia signaling cascade for erythropoietin production in hepatocytes. | | Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, Kawaguchi S, Takeda N, Takeda K, Fong GH, Dan T, Ichinose M, Miyata T, Yamamoto M, and Suzuki N. | Mol Cell Biol    35, 2658-2672  (2015) | 2014年卒業生、東條裕さんの論文です。 | |
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| Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon. | | Rajendran P, Dashwood WM, Li L, Kang Y, Kim E, Johnson G, Fischer KA, Löhr CV, Williams DE, Ho E, Yamamoto M, Lieberman DA, and Dashwood RH. | Clin Epigenetics    7, 102, eCollection  (2015) | | |
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| LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2. | | Takeuchi M, Fuse Y, Watanabe M, Andrea CS, Takeuchi M, Nakajima H, Ohashi K, Kaneko H, Kobayashi-Osaki M, Yamamoto M, and Kobayashi M. | Proc Natl Acad Sci USA   112, 13922-13927  (2015) | | |
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| The mediator subunit MED16 transduces NRF2-activating signals into antioxidant gene expression. | | Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, Igarashi K, Ito M, Motohashi H, and Yamamoto M. | Mol Cell Biol    36(3), 407-420  (2015) | | |
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| The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1. | | Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M. | Sci Signal   8, ra120  (2015) | | |
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